Wouter de Jonge
Wouter de Jonge (UU-Biomedical Sciences) was trained at Columbia University NY, University of Amsterdam (AMC) and the University of Maastricht and received his PhD in 2001, on the regulation of amino acid metabolism in the gut. During that time he became interested in neurogastroenterology, in particular in relation to gut innate immunology and host defence. He did a postdoc at Oxford University on macrophage physiology. He was/is funded by an EU FP7 Marie Curie grant (2006), a FEBS award (2006) and VIDI grant (2008), and several other non-personal grants. In 2009, he was appointed PI in the newly formed Tytgat Institute and laboratory of Gastroenterology and Hepatology, AMC (website: www.gut-research.com). Currently, his research focusses on neurogastroenterology and mucosal immunity. The gut immune cells have a high degree of tolerance towards commensal bacteria, and this is essential to prevent inflammatory disease. Research in de Jonge’s group aims to unravel this tolerant nature of mucosal immunity, and the dysregulation thereof in human GI disease. In addition, he is coordinating a joint EU project on epigenetics in mucosal immune cells in the context of IBD, in alliance with industry partner GSK (website: www.epimac.eu).
De Jonge aims to optimize the close merge between gastroenterologists, basic researchers and industrial partners from Life Science industry at the AMC setting. His group has long lasting collaborations with industrial partners in several projects involving pre-clinical and clinical evaluation of pipeline assets for human GI disease. His group studies gut inflammatory diseases (IBDs) as well as motility disorders (ileus, IBS).
The current research themes and directions of the group include intestinal immunity and nutrition, stress in relation to mucosal immunity, and nutrition and epithelial barrier function during health and disease. Correspondence on collaboration, or information of any kind is welcomed at: email@example.com